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BJA Advance Access published online on June 2, 2006
British Journal of Anaesthesia, doi:10.1093/bja/ael120
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© The Board of Management and Trustees of the British Journal of Anaesthesia 2006. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Postgraduate Issue Review Article

Depth of anaesthesia monitoring: what's available, what's validated and what's next?

J. Bruhn 1, P. S. Myles 2, R. Sneyd 3, and M. M. R. F. Struys 4 *

1 Department of Anesthesiology, University Hospital Bonn, Bonn, Germany
2 Anaesthesia and Perioperative Medicine, Monash University, Australia
3 Department of Anaesthesia, Peninsula Medical School, University of Plymouth, Plymouth, UK
4 Department of Anaesthesia and Heymans Institute of Pharmacology, Ghent University, Gent, Belgium

* To whom correspondence should be addressed.
M. M. R. F. Struys, E-mail: Michel.Struys{at}ugent.be


  Abstract

Depth of anaesthesia monitors might help to individualize anaesthesia by permitting accurate drug administration against the measured state of arousal of the patient. In addition, the avoidance of awareness or excessive anaesthetic depth might result in improved patient outcomes. Various depth of anaesthesia monitors based on processed analysis of the EEG or mid-latency auditory-evoked potentials are commercially available as surrogate measures of anaesthetic drug effect. However, not all of them are validated to the same extent.

Keywords: anaesthesia, depth; entropy; monitoring; BIS.
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