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British Journal of Anaesthesia 2006 96(2):152-155; doi:10.1093/bja/aei318
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© The Board of Management and Trustees of the British Journal of Anaesthesia 2006. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

EDITORIAL

Editorial II: Gabapentin: a new drug for postoperative pain?

D. J. Rowbotham

Leicester, UK

E-mail: Djr8@le.ac.uk

The first 10% of the full text of this article appears below.

Consistent delivery of first-class postoperative pain control is still a major challenge. Opioids are inevitably associated with emesis and the risk of respiratory depression, local anaesthetic techniques are often short-lived or require interventional procedures, and the use of NSAIDs and COX-2 inhibitors is limited by well known complications and concerns. Consider the possibility of a drug which significantly improves the quality of opioid analgesia, reduces opioid requirement, possibly prevents or reduces opioid tolerance and relieves anxiety. Furthermore, what if this drug did not depress respiration and had no effect on the gastric mucosa, platelets and renal function? A paper published in this edition of the British Journal of Anaesthesia1 and the work of others suggest that gabapentin may fit this profile.

. . . [Full Text of this Article]


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Gabapentin interactions to avoid
Michael I Carter
British Journal of Anaesthesia, 16 Feb 2006 [Full text]
Reply
David J Rowbotham
British Journal of Anaesthesia, 3 Mar 2006 [Full text]