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CORRESPONDENCE |
Contamination of anaesthetic gases with nitric oxide and its influence on oxygenation
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EditorI read with interest the article by Hess and colleagues1 and its accompanying editorial by Marczin2 on the effect of administration of compressed air (AIRc) or nitrous oxide on arterial
in ventilated patients, in comparison with a control period where synthetic air (AIRs) was used. The authors attributed a higher
to increased nitric oxide contaminating the former two mixtures.
The difference in
when receiving AIRc vs AIRs (0.5 kPa) was not clinically significant, as might be expected given that the nitric oxide levels with AIRc were much smaller than those used therapeutically to improve oxygenation.
The increase in
with nitrous oxide was much more significant (2.2 kPa or >15%). However, from the evidence available, it
Heidelberg, Victoria, Australia E-mail: phil.peyton@austin.org.au
E-mail: rikcarette@yahoo.com
1 Aalst, Belgium
2 Chicago, IL, USA
* E-mail: hessana@g-email.de
Hamburg, Germany