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British Journal of Anaesthesia 2004 93(2):178-180; doi:10.1093/bja/aeh175
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© The Board of Management and Trustees of the British Journal of Anaesthesia 2004

Editorial III: Corticosteroids for septic shock—a standard of care?

R. Bloomfield and D. W. Noble*

Intensive Care Unit, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN, UK

* Corresponding author. E-mail: david.noble@arh.grampian.scot.nhs.uk

The first 10% of the full text of this article appears below.

Septic shock has a crude mortality rate of 45% and claims the lives of 90 000 people each year in the USA alone.1 An epidemiological study from France of over 100 000 intensive care unit (ICU) admissions indicates the incidence of septic shock before or following admission to ICU is rising and now affects almost 10% of this patient population.2 Given the scale and associated costs of this problem,3 4 it is not surprising that developing solutions has been a focus of researchers, clinicians, and the pharmaceutical industry. Despite many past disappointments particularly with antagonists of endogenous mediators,5 some recent approaches have shown promise in prevention or treatment of sepsis . . . [Full Text of this Article]


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D. W. Noble
Dose Effects of Steroids on Survival in Sepsis
Ann Intern Med, December 7, 2004; 141(11): 891 - 891.
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