British Journal of Anaesthesia, 2003, Vol. 91, No. 5 755-756
© 2003 The Board of Management and Trustees of the British Journal of Anaesthesia
Correspondence |
Genes and outcome from anaesthesia
1 Copenhagen, Denmark 2 Bournemouth, UK
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EditorI would like to congratulate Dr Sweeney for the interesting Editorial.1 In it he describes, in some detail, the history of pharmacogenetics. He correctly points out that among the first documented accounts on genetic deficiencies responsible for a varied drug response were glucose-6-phosphate-dehydrogenase and N-acetyltransferase.2 3 However, he fails to report some early observations of far greater clinical impact for us as anaesthetists. About the same time as the