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British Journal of Anaesthesia, 2003, Vol. 91, No. 4 605-606
© 2003 The Board of Management and Trustees of the British Journal of Anaesthesia

Correspondence

Use of nitrous oxide in anaesthesia

L. Dimpel1 and M. Enlund2

1 Plymouth, UK 2 Västerås, Sweden

The first 10% of the full text of this article appears below.

Editor—Enlund and colleagues1 reported stopping the routine use of N2O in their department. Some of their theoretical considerations and their rhetorical question ‘has the value of N2O been overestimated?’ are begging for comment.

In 1990, Eger and colleagues2 found in an empirical study, that omission of N2O increased isoflurane requirements only marginally—from an average of 0.64% with N2O 60% to 0.85% without.

The value of N2O, added to a halogenated vapour, is usually thought of in terms of 'MAC reduction' of that vapour. Therefore, Enlund and colleagues anticipated that for every 10% N2O, the concentration of vapour . . . [Full Text of this Article]


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