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British Journal of Anaesthesia, 2003, Vol. 91, No. 3 445-446
© 2003 The Board of Management and Trustees of the British Journal of Anaesthesia


Correspondence

HIT/HITT and alternative anticoagulation: current concepts

David J. W. Knight1, D. Selwyn1, K. Girling1, S. Lakshmanan2, B. Saha2, D. Rittoo2, E. Pravinkumar3 and N. R. Webster3

1 Nottingham, UK 2 Manchester, UK 3 Aberdeen, UK

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Editor—We read with interest the Editorial by Pravinkumar and Webster,1 but were disappointed that the authors did not expand on heparin-induced thrombocytopenia (HIT)-rate-reduction by empiric use of low molecular weight heparin (LMWH). Many of the traditional uses of unfractionated heparin (UFH) have been superceded by the introduction of LMWH, including treatment of deep venous thrombosis, pulmonary embolism, and acute coronary syndromes. One of the under-explored therapeutic indications of LMWH is as the anticoagulant of choice for critically ill patients requiring continuous veno-venous haemofiltration (CVVH). We recently reported our experience in 52 consecutive patients to the Intensive Care Society of Great Britain.2

Traditionally, it is believed that LMWH has a lower HIT rate than . . . [Full Text of this Article]


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R. A. Saad, E. Pravinkumar, and N. R. Webster
HIT/HITT and alternative anticoagulation: current concepts
Br. J. Anaesth., October 1, 2003; 91(4): 606 - 607.
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