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British Journal of Anaesthesia, 2003, Vol. 91, No. 2 292-294
© 2003 The Board of Management and Trustees of the British Journal of Anaesthesia

Case Reports

Management of transfusion-related acute lung injury with extracorporeal cardiopulmonary support in a four-year-old child

S. M. Nouraei*,1, J. P. Wallis2, D. Bolton1 and A. Hasan1

1 Regional Cardiothoracic Centre, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK. 2 Department of Haematology, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK

Corresponding author: smnouraei@yahoo.co.uk

We report a case of successful management of transfusion-related acute lung injury (TRALI) with prolonged cardiopulmonary bypass support in a 4-yr-old patient undergoing elective cardiac surgery. TRALI was diagnosed clinically and immunologically by detection of reactive antibodies in a unit of fresh frozen plasma that had been administered to the patient. The aetiology and management of TRALI are briefly discussed and possible implications of this case for the management of TRALI are highlighted.

Br J Anaesth 2003; 91: 292–4


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