Skip Navigation

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (3)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Johi, R. R.
Right arrow Articles by Hansbro, S. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Johi, R. R.
Right arrow Articles by Hansbro, S. D.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, 2003, Vol. 90, No. 4 499-501
© 2003 The Board of Management and Trustees of the British Journal of Anaesthesia

Short Communications

Near-patient testing for coagulopathy after cardiac surgery{dagger}

R. R. Johi1, M. H. Cross1 and S. D. Hansbro2

1 Department of Anaesthesia and 2 Department of Clinical Perfusion, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK

Corresponding author. E-mail: michael.cross@leedsth.nhs.uk
{dagger}This article is accompanied by Editorial I.

Background. We assessed the accuracy and precision of a new near-patient testing system (Hemochron® Response) by measuring prothrombin time and activated partial thromboplastin time (PT and APTT) in 50 patients undergoing cardiac surgery using cardiopulmonary bypass and comparing the results with laboratory assays.

Methods. Blood samples were taken at the beginning of surgery and the PT and APTT was measured both in the laboratory and by the Hemochron® Response. The tests were repeated 30 min after reversal of heparin with protamine.

Results. Before bypass, the bias for PT was only +0.34, with small 95% limits of agreement. Making the same measurements after bypass, the Hemochron® Response under-read and the bias was –3.27, with an increase of the 95% limits of agreement. With the APTT, the bias and the 95% limits of agreement were greater before bypass, and became even wider after bypass.

Conclusions. We found good agreement in the PT and clinically acceptable levels of agreement in the APTT during the pre-bypass period. After bypass, bias became greater for both PT and APTT and the limits of agreement could be clinically unacceptable.

Br J Anaesth 2003; 90: 499–501


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Contin Educ Anaesth Crit Care PainHome page
A. N. Curry and J. T. Pierce
Conventional and near-patient tests of coagulation
CEACCP, April 1, 2007; 7(2): 45 - 50.
[Full Text] [PDF]

Home page
 Br J AnaesthHome page
U. R. Jahn and H. Van Aken
Editorial I: Near-patient testing--point-of-care or point of costs and convenience?
Br. J. Anaesth., April 1, 2003; 90(4): 425 - 427.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.