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British Journal of Anaesthesia, 2003, Vol. 90, No. 3 395-396
© 2003 The Board of Management and Trustees of the British Journal of Anaesthesia


Correspondence

Pathophysiology and clinical implications of perioperative fluid excess

G. Mitchell1, T. Hucker1, R. Venn1, H. Wakeling1, L. Forni1, J. Sartain2, K. Holte3, N. E. Sharrock3 and H. Kehlet3

1 Worthing, UK 2 Cairns, Australia 3 Hvidorre, Denmark

The first 10% of the full text of this article appears below.

Editor—We read with interest the review concerning the pathophysiology and clinical implications of perioperative fluid excess.1 However, we were surprised and have to disagree with the conclusion that there is a need for randomized, prospective clinical studies to compare ‘high’ vs ‘low’ fluid regimens. We were ‘surprised’ because the authors highlighted two excellent studies where appropriate plasma volume expansion resulted in significantly better gastrointestinal perfusion, and reductions in morbidity and hospital stay,2 3 and . . . [Full Text of this Article]


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