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British Journal of Anaesthesia, 2003, Vol. 90, No. 2 251-252
© 2003 The Board of Management and Trustees of the British Journal of Anaesthesia

Correspondence

Effect of hypothermia on brain tissue oxygenation in patients with severe head injury

P. Andrews1 and A. K. Gupta2

1 Edinburgh, UK 2 Cambridge, UK

The first 10% of the full text of this article appears below.

Editor—The interesting article1 on the effect of temperature on brain tissue partial pressure of oxygen appears to be methodologically flawed. A predictable, physically determined relationship between tissue PO2 and temperature is shown that is expected from basic physical principles, and not from exacerbation of a pathophysiological process.

The aim of this observational study by Gupta and colleagues was to determine the effect of a reduction in brain parenchymal temperature on brain tissue PO2. This is an important question to answer, and the investigators correctly measured brain temperature directly and did not infer it from body temperature measurements. The Paratrend 7 (Diametrics Medical, High Wycombe, . . . [Full Text of this Article]


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