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British Journal of Anaesthesia, 2003, Vol. 90, No. 1 101-105
© 2003 The Board of Management and Trustees of the British Journal of Anaesthesia

Correspondence

Exhaled nitric oxide as a marker of lung injury in coronary artery bypass surgery

N. Marczin1, T. Kövesis1, D. Royston1, B. H. Cuthbertson2, S. A. Stott2 and N. R. Webster2

1 Harefield, UK 2 Aberdeen, UK

The first 150 words of the full text of this article appear below.

Editor—We read with interest the publication by Cuthbertson and colleagues1 concerning exhaled nitric oxide as a marker of lung injury in coronary artery bypass surgery. We are particularly interested in this work.

We have been pursuing a similar area of research and published a series of observations in this field regarding exhaled nitric oxide and lung injury in the setting of heart surgery and transplantation during the last 5 yr.2–9 In addition, the work of Cuthbertson and colleagues appears to support our opinions expressed in the editorial: nitric oxide as mediator, marker and modulator of lung injury.10

We find that the potentially important article by the Aberdeen group contains intriguing data that require further clarification. This is related largely to the methodology, which appears to have important effects on the data obtained and its interpretation. As this is largely attributable to influence of ventilation parameters on exhaled nitric oxide concentrations, . . . [Full Text of this Article]


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