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British Journal of Anaesthesia, 2002, Vol. 89, No. 6 925-927
© 2002 The Board of Management and Trustees of the British Journal of Anaesthesia

Case Reports

Intrathecal morphine overdose during combined spinal–epidural block for Caesarean delivery

M. Cannesson, N. Nargues, B. Bryssine, R. Debon, E. Boselli and D. Chassard*

Service d’Anesthésie-Réanimation, Hôpital de l’Hôtel-Dieu, F-69002 Lyon, France

We describe a 25 mg intrathecal morphine overdose during a combined spinal–epidural block for a Caesarean delivery. Naloxone infusion (5.24 mg over 24 h) was started prior to the patient becoming symptomatic and almost immediately after the overdose. Invasive therapeutics such as mechanical ventilation were avoided.

Br J Anaesth 2002; 89: 925–7


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