Skip Navigation

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (15)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Müller, M.
Right arrow Articles by Albrecht, D. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Müller, M.
Right arrow Articles by Albrecht, D. M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, 2001, Vol. 87, No. 5 784-787
© 2001 The Board of Management and Trustees of the British Journal of Anaesthesia

Case Reports

Grand mal convulsion and plasma concentrations after intravascular injection of ropivacaine for axillary brachial plexus blockade

M. Müller, R. J. Litz, M. Hübler and D. M. Albrecht

Department of Anaesthesiology and Intensive Care Medicine, Carl Gustav Carus University Hospital, Dresden, Germany*Corresponding author: Department of Anaesthesiology and Intensive Care Medicine, Carl Gustav Carus University Hospital, Fetscherstrasse 74, D-01307 Dresden, Germany

We report a patient to whom ropivacaine 1.1 mg kg–1 was administered for brachial plexus blockade and who developed grand mal convulsions because of inadvertent i.v. injection. No symptoms of cardiovascular toxicity occurred. Venous blood samples were taken 15, 45, 75 and 155 min after the injection. The measured total plasma concentrations of ropivacaine were 3.3, 1.6, 1.2 and 1.0 mg litre–1 respectively. Initial plasma concentration after the end of the injection period was estimated at 5.75 mg litre–1 using a two-compartment pharmacokinetic model.

Br J Anaesth 2001; 87: 784–7


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Anesth. Analg.Home page
P. Cuvillon, E. Nouvellon, J. Ripart, J.-C. Boyer, L. Dehour, A. Mahamat, J. L'Hermite, C. Boisson, N. Vialles, J. Y. Lefrant, et al.
A Comparison of the Pharmacodynamics and Pharmacokinetics of Bupivacaine, Ropivacaine (with Epinephrine) and Their Equal Volume Mixtures with Lidocaine Used for Femoral and Sciatic Nerve Blocks: A Double-Blind Randomized Study
Anesth. Analg., February 1, 2009; 108(2): 641 - 649.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
T. Satsumae, M. Tanaka, S. Saito, and S. Inomata
Convulsions after ropivacaine 300 mg for brachial plexus block
Br. J. Anaesth., December 1, 2008; 101(6): 860 - 862.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
C. Robards, S. Clendenen, and R. Greengrass
Intravascular Injection During Ultrasound-Guided Axillary Block: Negative Aspiration Can Be Misleading
Anesth. Analg., November 1, 2008; 107(5): 1754 - 1755.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
R. J. Litz, T. Roessel, A. R. Heller, and S. N. Stehr
Reversal of Central Nervous System and Cardiac Toxicity After Local Anesthetic Intoxication by Lipid Emulsion Injection
Anesth. Analg., May 1, 2008; 106(5): 1575 - 1577.
[Abstract] [Full Text] [PDF]

Home page
 Arch Otolaryngol Head Neck SurgHome page
A. H. Park, A. L. Pappas, E. Fluder, S. Creech, R. A. Lugo, and A. Hotaling
Effect of Perioperative Administration of Ropivacaine With Epinephrine on Postoperative Pediatric Adenotonsillectomy Recovery
Arch Otolaryngol Head Neck Surg, April 1, 2004; 130(4): 459 - 464.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
M. Dernedde, D. Furlan, R. Verbesselt, E. Gepts, and J. G. Boogaerts
Grand Mal Convulsion After an Accidental Intravenous Injection of Ropivacaine
Anesth. Analg., February 1, 2004; 98(2): 521 - 523.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
J. C. Crews and T. E. Rothman
Seizure After Levobupivacaine for Interscalene Brachial Plexus Block
Anesth. Analg., April 1, 2003; 96(4): 1188 - 1190.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.