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British Journal of Anaesthesia, 2001, Vol. 87, No. 4 629-631
© 2001 The Board of Management and Trustees of the British Journal of Anaesthesia

Short Communications

Randomized prospective double-blind placebo-controlled trial of effect of intravenous ondansetron on intraocular pressure during ophthalmic surgery

N. M. Robin1 and S. M. Mostafa*

Department of Anaesthesia, Royal Liverpool University Hospital, Prescot Street, Liverpool L7 8XP, UK 1Present address: Department of Anaesthesia, Dandenong Hospital, Southern Health Care Network, Dandenong, Victoria 3175, Australia*Corresponding author

The effect of i.v. ondansetron, before induction of anaesthesia, on intraocular pressure (IOP) in patients undergoing cataract surgery was investigated. Forty patients (two groups of 20) received either ondansetron 4 mg (treatment group) or 0.9% saline (placebo group) in a double-blind controlled manner. There were no significant differences in IOP between the groups. Ondansetron had no significant effect on IOP during the study period.

Br J Anaesth 2001; 87: 629–31


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