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British Journal of Anaesthesia, 2001, Vol. 87, No. 4 531-533
© 2001 The Board of Management and Trustees of the British Journal of Anaesthesia

Editorial

Editorial I

Measuring the outcome of surgical procedures: what are the challenges?

F. Carli and N. Mayo

Hall and colleagues1 have presented an interesting study linking a number of physiological variables to outcomes in persons who have undergone hip arthroplasty. Presumably, the motivation for the study was to identify strategies to reduce the perioperative stress response, which would in turn aid recovery.

Essentially this study found that there was a relationship between the inflammatory response, as measured by interleukin 6 (IL-6) and the number of postoperative days before patients could walk 10 and 25 m independently. Outcomes 1 and 6 months after surgery, as measured by the WOMAC (a self-report pain and activity questionnaire with excellent psychometric properties), were not influenced by any of the physiological variables measured in the study. The endocrine response did not appear to influence either the short-term or the long-term outcome.

A question comes to mind in interpreting these findings. Is there a biological reason for suspecting that any of the postoperative physiological variables could . . . [Full Text of this Article]

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