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British Journal of Anaesthesia, 2001, Vol. 87, No. 2 316-319
© 2001 The Board of Management and Trustees of the British Journal of Anaesthesia


Case Reports

Another feature of TURP syndrome: hyperglycaemia and lactic acidosis caused by massive absorption of sorbitol

C. A. Trépanier1, M. R. Lessard1, J. Brochu1 and G. Turcotte2

1Department of Anesthesia and 2Department of Biochemistry, Centre hospitalier affilié universitaire de Québec (Hôpital Enfant-Jésus), Laval University, 1401, 18e Rue, Québec, PQ, G1J 1Z4 Canada*Corresponding author

Endoscopic transurethral resection of the prostate (TURP) can be complicated by absorption of a large volume of irrigation fluid. The clinical features of this complication are referred as the TURP syndrome. We report a case where hyperglycaemia and lactic acidosis complicated the TURP syndrome caused by the massive absorption (approximately 15 litres) of a sorbitol– mannitol irrigation solution. The proposed mechanism is a type B lactic acidosis related to the metabolism of sorbitol.

Br J Anaesth 2001; 87: 316–19


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