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British Journal of Anaesthesia, 2001, Vol. 86, No. 3 437-441
© 2001 The Board of Management and Trustees of the British Journal of Anaesthesia

Multiple acyl-CoA dehydrogenase deficiency: a rare cause of acidosis with an increased anion gap

A. S. Grice and T. E. Peck

Department of Anaesthetics, Poole General Hospital, Poole BH15 2JB, UK*Corresponding author

Metabolic acidosis is encountered frequently in intensive care and common causes include lactic acidosis, ketoacidosis, or renal failure. We describe a patient presenting to intensive care with a rare cause of metabolic acidosis associated with an increased anion gap: multiple acyl-CoA dehydrogenase deficiency. The pathophysiology of this condition is discussed along with potential treatment options.

Br J Anaesth 2000; 86: 437–41


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