British Journal of Anaesthesia, 2001, Vol. 86, No. 2 241-244
© 2001 The Board of Management and Trustees of the British Journal of Anaesthesia
Spinal anaesthesia with ropivacaine 5 mg ml1 in glucose 10 mg ml1 or 50 mg ml1
University Department of Anaesthesia, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK*Corresponding author
Forty patients undergoing spinal anaesthesia for a variety of surgical procedures were randomly allocated to receive 3 ml of ropivacaine 5 mg ml1 in glucose 10 mg ml1 or 50 mg ml1. Onset of sensory block to T10 was significantly faster (P=0.03) with the glucose 50 mg ml1 solution (median 5 min, range 220 min) than with the 10 mg ml1 solution (median 10 min, range 225 min). Maximum extent of cephalad spread was virtually the same in both groups (10 mg ml1 median T6/7, range T3T10; 50 mg ml1 median T6, range T3T10) with similar times to regression beyond S2 (10 mg ml1 median 210 min, range 150330 min; 50 mg ml1 median 210 min, range 150330 min). Complete motor block was produced in the majority of patients (10 mg ml1 90%; 50 mg ml1 85%) and the time to complete regression was the same in both groups (median 120 min, range 90210 min). A block adequate for the projected surgery was achieved in all patients.
Br J Anaesth 2001; 86: 2414
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