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British Journal of Anaesthesia, 2001, Vol. 86, No. 2 164-166
© 2001 The Board of Management and Trustees of the British Journal of Anaesthesia

Editorial

Editorial II

Is peri-operative renal dysfunction of no consequence?

M. L. Cittanova

Post-operative renal dysfunction has long been considered to be a relatively minor event, since its effect on the immediate prognosis of the patient is not evident. Thus, a transient increase in serum creatinine in the post-operative period was regarded as being of little relevance to clinical outcome. Ronco and Flahault1 highlighted the impact of cumulative renal injuries from various life events, such as nephrotoxic drugs or peri-operative renal insult, which may ultimately lead to irreversible renal injury. Svensson and colleagues2 had suggested previously that a post-operative increase in serum creatinine of above 180 µmol litre–1, frequently considered as negligible, was associated with an increase in late mortality from 30% to 50% 5 yr after major aortic surgery. Moreover, a recent study by Chertow and colleagues3 has demonstrated clearly that post-operative acute . . . [Full Text of this Article]

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