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British Journal of Anaesthesia, 2001, Vol. 86, No. 1 141-142
© 2001 The Board of Management and Trustees of the British Journal of Anaesthesia

Paradoxical changes in bispectral index during nitrous oxide administration

G. D. Puri

Department of Anesthesiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India 160012

I report two patients undergoing open heart surgery, with nitrous oxide and isoflurane anaesthesia, for whom bispectral index (BIS) monitoring showed high BIS values with nitrous oxide and isoflurane anaesthesia. The BIS decreased immediately after nitrous oxide was stopped and increased again after nitrous oxide was restarted.

Br J Anaesth 2001; 86: 141–2


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