Skip Navigation

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (9)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Lichtwarck-Aschoff, M.
Right arrow Articles by Guttmann, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lichtwarck-Aschoff, M.
Right arrow Articles by Guttmann, J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, 2000, Vol. 85, No. 4 577-586
© 2000 The Board of Management and Trustees of the British Journal of Anaesthesia

Static versus dynamic respiratory mechanics for setting the ventilator

M. Lichtwarck-Aschoff1,*, V. Kessler2, U. H. Sjöstrand3, A. Hedlund4, G. Mols2, S. Rubertsson3, A. M. Markström5 and J. Guttmann2

1Department of Anesthesiology and Intensive Care, University Hospital, Uppsala, Sweden and Zentralklinikum Augsburg, Germany. 2Department of Anesthesiology and Critical Care Medicine, University of Freiburg, Freiburg, Germany. 3Department of Anesthesiology and Intensive Care, University Hospital, Uppsala, Sweden. 4Department of Plastic Surgery, University Hospital, Uppsala, Sweden. 5Department of Anesthesiology and Intensive Care and Dept of Otorhinolaryngology University Hospital, Uppsala, Sweden

The lower inflection point (LIP) of the inspiratory limb of a static pressure-volume (PV) loop is assumed to indicate the pressure at which most lung units are recruited. The LIP is determined by a static manoeuvre with a PV-history that is different from the PV-history of the actual ventilation. In nine surfactant-deficient piglets, information to allow setting PEEP and VT was obtained, both from the PV-curve and also during ongoing ventilation from the dynamic compliance relationship. According to LIP, PEEP was set at 20 (95% confidence interval 17–22) cm H2O. Volume-dependent dynamic compliance suggested a PEEP reduction (to 15 (13–18) cm H2O). Pulmonary gas exchange remained satisfactory and this change resulted in reduced mechanical stress on the respiratory system, indirectly indicated by volume-dependent compliance being consistently great during the entire inspiration.

Br J Anaesth 2000; 85: 577–86

* Corresponding author: Klinik für Anaesthesiologie und Operative Intensivmedizin am Zentralklinikum Augsburg, Stenglinstr. 2, D-86156 Augsburg, Germany


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Toxicol SciHome page
K. M. Kransler, B. P. McGarrigle, D. D. Swartz, and J. R. Olson
Lung Development in the Holtzman Rat is Adversely Affected by Gestational Exposure to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin
Toxicol. Sci., February 1, 2009; 107(2): 498 - 511.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
G. Mols, H.-J. Priebe, and J. Guttmann
Alveolar recruitment in acute lung injury
Br. J. Anaesth., February 1, 2006; 96(2): 156 - 166.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
O. Stenqvist
Practical assessment of respiratory mechanics
Br. J. Anaesth., July 1, 2003; 91(1): 92 - 105.
[Full Text] [PDF]

Home page
 Br J AnaesthHome page
G. Mols, V. Kessler, A. Benzing, M. Lichtwarck-Aschoff, K. Geiger, and J. Guttmann
Is pulmonary resistance constant, within the range of tidal volume ventilation, in patients with ARDS?
Br. J. Anaesth., February 1, 2001; 86(2): 176 - 182.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.