Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (27)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Stahle, L.
Right arrow Articles by Hahn, R. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Stahle, L.
Right arrow Articles by Hahn, R. G.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, Vol 78, Issue 2 138-143, Copyright © 1997 by The Board of Management and Trustees of the British Journal of Anaesthesia

CLINICAL INVESTIGATIONS

Modelling the volume of expandable body fluid spaces during i.v. fluid therapy

L. Stahle, A. Nilsson and R. G. Hahn
Department of Clinical Pharmacology, Huddinge University Hospital, S-141 86 Huddinge, Sweden; Astra Human Pharmacology, Huddinge University Hospital, S-141 86 Huddinge, Sweden; Department of Anaesthesia, Soder Hospital, S-118 83 Stockholm, Sweden

We have developed mathematical models to represent the changes in volume of fluid spaces associated with i.v. administration of a crystalloid solution. Input data for parameter estimations were dilution of blood, measured as reduction of blood haemoglobin concentration. The models were based on the assumption that the body strives to maintain volume homeostasis of fluid spaces and that the rate of restoration is a function of deviation from resting volume. Two models were derived; the first had a single fluid space into which fluid was administered and from which fluid left, the other model had a second fluid space communicating with the first. These models may be useful in the description and analysis of the effects of i.v. fluid therapy.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Anesth. Analg.Home page
D. R. McIlroy and E. D. Kharasch
Acute Intravascular Volume Expansion with Rapidly Administered Crystalloid or Colloid in the Setting of Moderate Hypovolemia
Anesth. Analg., June 1, 2003; 96(6): 1572 - 1577.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
R. G. Hahn, G. C. Kramer, D. S. Prough, and S. Tollofsrud
Physiological or Functional Fluid Spaces * Response
Anesth. Analg., July 1, 2002; 95(1): 251 - 252.
[Full Text] [PDF]

Home page
 Anesth. Analg.Home page
S. Tollofsrud, G. I. Elgjo, D. S. Prough, C. A. Williams, D. L. Traber, and G. C. Kramer
The Dynamics of Vascular Volume and Fluid Shifts of Lactated Ringer's Solution and Hypertonic-Saline-Dextran Solutions Infused in Normovolemic Sheep
Anesth. Analg., October 1, 2001; 93(4): 823 - 831.
[Abstract] [Full Text] [PDF]

Home page
 Innate ImmunityHome page
C. Svensen, H. Hjelmqvist, and R. G. Hahn
Volume kinetics of Ringer solution during endotoxinemia in conscious rabbits
Innate Immunity, December 1, 1997; 4(6): 425 - 430.
[Abstract] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.