British Journal of Anaesthesia, Vol 76, Issue 6 767-771, Copyright © 1996 by The Board of Management and Trustees of the British Journal of Anaesthesia
O. A. Meretoja, T. Taivainen, L. Raiha, R. Korpela and K. Wirtavuori
We have studied 120 infants and children, in three age groups (3-11 months,
1-5 yr and 6-15 yr), to compare anaesthesia with sevoflurane or halothane
for bronchoscopy or gastroscopy, or both. Premedication or i.v. anaesthetic
agents were not used. Patients were allocated randomly to receive either 7%
sevoflurane or 3% halothane in 66% nitrous oxide in oxygen for induction of
anaesthesia. The same inspired mixture was continued during bronchoscopy
while the concentration of the inhalation agent was reduced by 50% during
gastroscopy. Induction times were shorter for infants than for children and
shorter for sevoflurane than for halothane. Cardiac arrhythmias were
significantly more frequent during halothane than during sevoflurane
anaesthesia. Physiological and psychomotor recovery were more rapid after
sevoflurane than after halothane. At 24-h follow-up, children who received
sevoflurane had significantly less nausea and vomiting. We conclude that
sevoflurane was superior to halothane for paediatric bronchoscopy and
gastroscopy.
CLINICAL INVESTIGATIONS
Sevoflurane-nitrous oxide or halothane-nitrous oxide for paediatric bronchoscopy and gastroscopy
Department of Anaesthesiology, Children's Hospital University of Helsinki, FIN-00290 Helsinki, Finland
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