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British Journal of Anaesthesia, Vol 76, Issue 2 245-250, Copyright © 1996 by The Board of Management and Trustees of the British Journal of Anaesthesia

CLINICAL INVESTIGATIONS

Fuzzy logic control of inspired isoflurane and oxygen concentrations using minimal flow anaesthesia

M. Curatolo, M. Derighetti, S. Petersen-Felix, P. Feigenwinter, M. Fischer and A. M. Zbinden
Institute of Anaesthesiology and Intensive Care, Section of Research, University of Bern, Inselspital, 3010 Bern, Switzerland; Automatic Control Laboratory, Swiss Federal Institute of Technology, Zurich, Switzerland

In order to evaluate the performance of feedback fuzzy logic control of inspired oxygen and isoflurane concentrations, we studied 30 patients undergoing discectomy for lumbar (n = 26) or cervical (n = 4) disc herniation. Patients were allocated random to one of two groups: a standard group (n = 15) with low flow anaesthesia (1.2-1.3 litre min-1) and manual control of gas concentrations; and a fuzzy group (n = 15) with minimal flow (0.5 litre min-1) and fuzzy logic feedback control of gas concentrations. Fuzzy logic control achieved and maintained very accurately the desired isoflurane concentration. Oxygen concentration was controlled more precisely than in the standard group. Delivery and costs of oxygen and nitrous oxide were significantly lower in the fuzzy group (P < 0.01). Accumulation of foreign gases was observed in one patient during low flow and in 11 patients during minimal flow anaesthesia. In conclusion, fuzzy logic control of inspired oxygen and isoflurane concentration during minimal flow anaesthesia was reliable and reduced anaesthetic gas delivery and costs.
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