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British Journal of Anaesthesia, 1995, Vol. 74, No. 4 458-460
© 1995 The Board of Management and Trustees of the British Journal of Anaesthesia

other

Extradural ropivacaine and bupivacaine in hip surgery

A. P. WOLFF, MD*, L. HASSELSTRÖM, MD, H. E. KERKKAMP, MD, PHD and M. J. GIELEN, MD, PHD

Sint Anna Hospital, Joannes Zwijsenlaan 121, NL-5342 BT, Oss, The Netherlands and University Hospital of Nijmegen The Netherlands
Randers Central Hospital DK-8900 Randers, Denmark
Canisius-Wilhelmina Hospital Weg door Jonkerbos 100, NL-6500 GS Nijmegen, The Netherlands
Institute of Anaesthesia, University Hospital of Nijmegen Geert Grooteplein Zuid 10, NL 6500 HB, Nijmegen, The Netherlands

*Address for correspondence: Institute of Anaesthesia, University Hospital of Nijmegen, Postbus 9101, NL-6500 HB Nijmegen, The Netherlands

We studied 126 patients undergoing elective hip surgery; they received 20 ml of 0.5%, 0.75%, 1.0% ropivacaine or 0.5% bupivacaine extradurally in a double-blind design. Sensory block (pinprick), motor block (modified Bromage scale), quality of analgesia and neuromuscular block were assessed intermittently. Heart rate and arterial pressure were measured at regular intervals. A total of 115 patients were evaluated for efficacy. Onset of analgesia, onset of motor block and maximum cephalad spread (T4) did not differ between the groups. Duration and quality of analgesia and motor block increased with the concentration of ropivacaine. Ropivacaine 1.0% provided a longer duration of analgesia and motor block, more intense motor block and more patients with satisfactory analgesia than 0.5% bupivacaine. More patients treated with the higher concentrations of ropivacaine required treatment for hypotension and bradycardia.


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