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British Journal of Anaesthesia, 1991, Vol. 66, No. 1 129-130
© 1991 The Board of Management and Trustees of the British Journal of Anaesthesia

other

METOCLOPRAMIDE AND RENAL VASCULAR RESISTANCE

A. R. MANARA, M.R.C.P., F.C.ANAES.*, S. BOLSIN, F.C.ANAES., C. R. MONK, F.C.ANAES, G. HARTNELL, F.R.C.R. and R. A. HARRIS, M.SC.

Sir Humphry Davy Department of Anaesthesia, Bristol Royal Infirmary Marlborough Street, Bristol BS2 8HW
University Department of Radiodiagnosis, Bristol Royal Infirmary Marlborough Street, Bristol BS2 8HW
Department of Medical Physics, Bristol General Hospital Guinea Street, Bristol BS1 6SY

*Present address, for correspondence: Department of Anaesthesia, Frenchay Hospital, Bristol BS16 1LE.

We have studied the effect of i. v. metoclopramide on renal vascular resistance in nine healthy volunteers. Peak systolic and end-diastolic frequencies were measured using duplex Doppler ultrasound of a renal interlobar artery, before and after the administration of i.v. metoclopramide 10 mg, and the resistance index derived. There was no significant change in mean arterial pressure or resistance index following metoclopramide.


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