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British Journal of Anaesthesia, 1989, Vol. 63, No. 5 558-560
© 1989 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

EFFECT OF ANAESTHESIA ON THE QT INTERVAL

I. McCONACHIE, M.B., CH.B., F.F.A.R.C.S., J. P. KEAVENY, M.B., CH.B., F.F.A.R.C.S., T. E. J. HEALY, M.SC., M.D., F.F.A.R.C.S., S. VOHRA, M.B., CH.B., F.F.A.R.C.S. and L. MILLION, M.SC.

University Department of Anaesthesia, University of Manchester, Withington Hospital Manchester M20 8LR

A prolonged electrocardiographic QT interval may be harmful during general anaesthesia. It may be prudent, therefore, to select anaesthetic agents which have the least effect on the QT interval. In a controlled study, propofol has been shown to have less effect on the QT interval than thiopentone (P < 0.05). Our data suggest also that any effects which may be caused by enflurane and isoflurane are masked by the effects of the induction agent.


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