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British Journal of Anaesthesia, 1989, Vol. 62, No. 2 210-212
© 1989 The Board of Management and Trustees of the British Journal of Anaesthesia

case-report

PANCURONIUM ALLERGY: A CASE REPORT

G. PATRIARCA, M.D., E. NUCERA, M.D., D. SCHIAVINO, M.D., A. ROMANO, M.D., V. DI RIENZO, M.D., S. PELLEGRINO, M.D. and G. FAIS, M.D.

Department of Allergology, Catholic University Largo Gemelli, 8 00168 Rome, Italy

A case of anaphylactic shock to pancuronium bromide is described in which a type l immunological reaction occurred. A 33-yr-old male anaesthetist, with no family or personal history of allergy, collapsed soon after induction of anaesthesia. The drugs used included fentanyl, droperidol, thiopentone and pancuronium. Diffuse erythema occurred, with probable cardiac arrest. The patient was treated with cardiac massage, sympathomimetics and cortisone, and made a complete recovery. Examination (skin tests, passive transfer according to Prausnitz and Küstner, in vitro lymphocyte transformation test, total lgE assay) revealed that the allergic reaction was to pancuronium bromide.


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R. P. Mahajan and J. M. Hunter
Volume 100: Case reports: should they be confined to the dustbin?
Br. J. Anaesth., June 1, 2008; 100(6): 744 - 746.
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