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British Journal of Anaesthesia 2009 103(1):135-137; doi:10.1093/bja/aep155
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© The Author [2009]. Published by Oxford University Press on behalf of The Board of Directors of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournal.org

Response entropy–state entropy difference and nociception: a matter of context

D. M. Mathews

New York, USA

E-mail: dmathews@svcmcny.org

The first 10% of the full text of this article appears below.

Editor—Aho and colleagues1 concluded that ‘response entropy (RE)–state entropy (SE) difference cannot reliably be used as an indicator of nociception in patients anaesthetized with propofol, nitrous oxide and remifentanil without neuromuscular blocking drugs’. This statement should be qualified by adding ‘when the values are averaged over 15 s and measured in a state of anaesthesia inadequate for the level of noxious stimulation’.

The authors reached their conclusion based on the observation that the entropy difference after intubation was not different between patients with and without remifentanil. This was because, in both groups, while the RE increased immediately with . . . [Full Text of this Article]

Declaration of interest

A. J. Aho*, A. Yli-Hankala, L.-P. Lyytikäinen and V. Jäntti

Tampere, Finland

* E-mail: antti.j.aho@uta.fi

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