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Acidosis, phosphofructokinase, and diabetic coma
Bratislava, Slovakia
E-mail: rosivalv@hotmail.com
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Editor—In their recent article, Handy and Soni1 propose that With regard to acidosis, the clinical literature is remarkable in its lack of conclusive evidence to support the perception that the acidosis itself is a detrimental state in need of direct correction.
However, they have omitted the paper of Edge and colleagues2 which has shown that low blood pH is the immediate cause of coma.
London, UK
E-mail: j.m.handy@imperial.ac.uk