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British Journal of Anaesthesia 2008 100(2):278-279; doi:10.1093/bja/aem381
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© The Board of Management and Trustees of the British Journal of Anaesthesia 2008. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Sevoflurane and cardioprotection

L. Siracusano* and V. Girasole

Messina, Italy

* E-mail: lsiracusano@unime.it

The first 10% of the full text of this article appears below.

Editor—We read with interest the study by Piriou and colleagues1 who observed limited cardioprotection after 1 MAC sevoflurane in humans undergoing cardiopulmonary bypass (CPB). Julier2 obtained similar results by a higher concentration of sevoflurane (2 MAC) given for 10 min through a vaporizer integrated into the CPB machine. Julier but not Piriou observed PKC translocation in the myocardium, an event related to the protection conferred by preconditioning.3 However, a protective . . . [Full Text of this Article]

V. Piriou* and J. Mantz

Lyon, France

* E-mail: piriou@univ-lyon1.fr


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