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British Journal of Anaesthesia 2005 95(1):110; doi:10.1093/bja/aei567
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© The Board of Management and Trustees of the British Journal of Anaesthesia 2005. All rights reserved. For Permissions, please e-mail: journal.permissions@oupjournals.org

CORRESPONDENCE

‘Paedfusor’ pharmacokinetic data set

* E-mail: anthony.absalom{at}addenbrookes.nhs.uk

Editor—Recently, several ‘open TCI’ systems (target-controlled infusion devices not requiring pre-filled propofol syringes) have been developed. In the near future some manufacturers of these systems will distribute such systems programmed with other pharmacokinetic data sets for propofol, and also data sets for other drugs such as remifentanil. One such set is the ‘Paedfusor’ pharmacokinetic data set for children. When we published the results of a study of the predictive performance of this data set, for brevity we did not publish the full pharmacokinetic details. We also omitted the non-linear kinetics used for children aged 13–16 yr.1 2 For the benefit of those who wish to use this model we have provided the full details in Table 1.


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  		Table 1 ‘Paedfusor’ propofol pharmacokinetic data set

 
A. Absalom1,* and G. Kenny2

1 Cambridge, UK
2 Glasgow, UK

References

1 Amutike D, Lal A, Absalom AR, Kenny GNC. Accuracy of the Paedfusor—a new propofol target-controlled infusion system for children. Br J Anaesth 2001; 87: 175–6P

2 Absalom AR, Amutike D, Lal A, White M, Kenny GN. Accuracy of the ‘Paedfusor’ in children undergoing cardiac surgery or catheterization. Br J Anaesth 2003; 91: 507–13[Abstract/Free Full Text]


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This Article
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