British Journal of Anaesthesia, 2003, Vol. 91, No. 1 81-91
© 2003 The Board of Management and Trustees of the British Journal of Anaesthesia
Review Article |
Novel aspects of pulmonary mechanics in intensive care
Room 8-62 Stabile Building, Mayo Clinic, Rochester, MN 55905, USA
Corresponding author. E-mail: rhubmayr@mayo.edu
Keywords: intensive care; ventilation, mechanics
| The first 150 words of the full text of this article appear below. |
This review of the mechanical properties of the respiratory system is related to ventilator practice. As virtually all modern ventilators display traces of airway pressure (Paw), volume (V) and flow (V·) the necessary information is immediately available with no additional effort. This review interprets the information contained in ventilator waveforms. The review concentrates on three aspects where measurements are most useful, namely: (i) the diagnosis and management of patients with injured lungs; (iii) patients with airways obstruction; and (iii) the assessment of respiratory motor output. We will outline the precision and accuracy of the derived variables, discuss their scientific basis and review how decisions based on these measurements improve patient outcomes. We give a personal perspective even if it means taking sides in debates on controversial issues.
Basic principles
(For a full discussion of classic respiratory system mechanics the reader is referred to refs 6 and 47). Classic respiratory
Assessment of respiratory mechanics in the diagnosis and management of patients with injured lungs
Injury mechanisms and their consequences on lung mechanics
Susceptibility of injured lungs to VILI
Whole respiratory system mechanics: methods and mechanistic interpretation
Role of respiratory mechanics testing in clinical decision-making
Assessment of respiratory mechanics in patients with airflow obstruction
Basic principles for identifying airway obstruction in a mechanically ventilated patient
The bedside diagnosis of obstruction in mechanically ventilated patients
Inadvertent PEEP
Inspection of expiratory flowvolume and flow-time tracings
Inspection of the Paw tracing (Fig. 5)
The peak Paw response to small step changes in PEEP (Fig. 6)
Clinical implications of respiratory mechanics measurements in patients with obstruction
Value of respiratory mechanics in the assessment of respiratory drive and timing
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