Editorial I: Variant Creutzfeldt-Jakob disease and disposable anaesthetic equipment--balancing the risks

doi:10.1093/bja/aeg006

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British Journal of Anaesthesia, 2003, Vol. 90, No. 1 1-3
© 2003 The Board of Management and Trustees of the British Journal of Anaesthesia

Editorial

Editorial I

Variant Creutzfeldt–Jakob disease and disposable anaesthetic equipment—balancing the risks

M. C. Blunt^*^,1 and K. R. Burchett¹

¹ Department of Anaesthesia and Critical Care, Queen Elizabeth Hospital, Gayton Road, Kings Lynn PE30 4ET, UK *E-mail: markblunt@eaicg.com

LMA^® is the property of Intavent Limited.

The first 150 words of the full text of this article appear below.

New variant Creutzfeldt–Jakob disease (vCJD) was firstreported in the UK in 1996.¹ By August 2002, a total of 125cases of definite or probable vCJD had been identified in theUK, six in France, one in Italy, one in Florida and one in theRepublic of Ireland.² vCJD is one of a class of diseases knownas transmissible spongiform encephalopathies (TSEs), which includescrapie in sheep and bovine spongiform encephalopathy (BSE)in cattle. TSEs are fatal degenerative brain diseases that arecharacterized by rapidly progressive dementia and a spongy macroscopicappearance of brain tissue. The infective agents appear to bemisshapen prion proteins. It is thought that the misshapen prionproteins (PrP^SC) can cause further distortion of the normalform of the prion protein (PrP^C), leading to a chain reactionthat propagates the disease and generates new infectious material.³This infectious agent is resistant to methods of . . . [Full Text of this Article]

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