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British Journal of Anaesthesia, 2002, Vol. 89, No. 6 807-810
© 2002 The Board of Management and Trustees of the British Journal of Anaesthesia

Editorial

Editorial I

Confidence in statistical analysis

T. Asai1

1 Department of Anaesthesiology, Kansai Medical University, Osaka 570-8507, Japan E-mail: asait@takii.kmu.ac.jp

The first 150 words of the full text of this article appear below.

In this era of evidence-based medicine, randomized controlled trials are crucial sources for making clinical decisions. But what should we expect from a randomized controlled trial? First of all, we would like to know if there is a difference between treatments—for example, if a new drug is better than an old one. As we cannot obtain data from the entire population, we set up a randomized controlled trial on a sample of subjects and apply each treatment to a different group. We will almost certainly find some difference between the groups, because even if the same treatment had been applied to both groups we would be very likely to have some difference because of the variability between subjects in their response to the treatment. So, how do we know whether the observed difference is a reflection of a systematic difference in the population as a whole or just a reflection . . . [Full Text of this Article]


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Home page
 Br J AnaesthHome page
O. Sanehi and T. Asai
Confidence in statistical analysis
Br. J. Anaesth., May 1, 2003; 90(5): 706 - 706.
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