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British Journal of Anaesthesia 2009 102(5):585-587; doi:10.1093/bja/aep080
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© The Author [2009]. Published by Oxford University Press on behalf of The Board of Directors of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournal.org

Acustimulation of P6: an antiemetic alternative with no risk of drug-induced side-effects

The first 10% of the full text of this article appears below.

Postoperative nausea and vomiting (PONV) is one of the most common complications after general anaesthesia, mainly triggered by inhalation anaesthetics and postoperative opioids.1 However, current medications for PONV have limited efficacy and may even be associated with potential side-effects. For example, severe cardiac arrhythmias reported in association with droperidol led the US Food and Drug Administration (FDA) to issue a black box warning.2 Even though droperidol prolongs the QTc interval, its clinical relevance remains controversial.3 As a consequence, haloperidol is increasingly used in the perioperative setting. Unfortunately, haloperidol has . . . [Full Text of this Article]

C. C. Apfel* and S. Kinjo

Perioperative Clinical Research Core
UCSF Cancer Center at Mount Zion
University of California San Francisco
1600 Divisadero, C447
San Francisco
CA 94115
USA

* E-mail: apfelc@anesthesia.ucsf.edu or apfel@ponv.org


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