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BJA Advance Access originally published online on October 17, 2007
British Journal of Anaesthesia 2007 99(6):837-844; doi:10.1093/bja/aem267
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© The Board of Management and Trustees of the British Journal of Anaesthesia 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Midlatency auditory evoked potentials in children: effect of age and general anaesthesia

M. Daunderer1,*, M. S. Feuerecker1, B. Scheller2, N. B. Pape1, D. Schwender3 and G. E. Kuhnle1

1 Clinic for Anaesthesiology, Ludwig Maximilians University Munich, Nussbaumstr. 20, D-80336 Munich, Germany
2 Clinic for Anaesthesiology, Johann Wolfgang v. Goethe University, Frankfurt, Germany
3 Department for Anaesthesiology, Clinic Friedrichshafen, Lake of Constance, Germany

* Corresponding author. E-mail: dr.daunderer{at}web.de

Background: Midlatency auditory evoked potentials (MLAEP) are a promising tool for monitoring suppression of sensory processing during anaesthesia and might help to avoid awareness. MLAEP in children are different to those in adults and the exact changes during general anaesthesia are unknown.

Methods: In 49 children of age between 2 and 12 yr, MLAEP were recorded before anaesthesia, during tracheal intubation, at steady-state balanced anaesthesia, and after extubation.

Results: MLAEP were recordable in all children in the awake (premedicated) state with latencies but not amplitudes dependent on children's age. MLAEP latencies significantly increased during tracheal intubation and steady-state anaesthesia. Changes in amplitudes were inconsistent. All MLAEP variables returned to near baseline values after extubation.

Conclusions: The results of this study imply that MLAEP can successfully be recorded during anaesthesia in children above the age of 2 yr. Further studies are necessary before MLAEP might be applicable for monitoring purposes in paediatric anaesthesia.

Keywords: anaesthesia, general; anaesthesia, paediatric; anaesthetics, volatile; monitoring, depth of anaesthesia; monitoring, evoked potentials


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