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BJA Advance Access originally published online on August 3, 2007
British Journal of Anaesthesia 2007 99(4):514-517; doi:10.1093/bja/aem213
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© The Board of Management and Trustees of the British Journal of Anaesthesia 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Prolonged residual paralysis after a single intubating dose of rocuronium

C. Claudius*, H. Karacan and J. Viby-Mogensen

Department of Anaesthesia and Intensive Care, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark

* Corresponding author: Department of Anaesthesia and Intensive Care 4231, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark. E-mail: casperclaudius{at}dadlnet.dk

It is often argued that neuromuscular monitoring is unnecessary when only one dose of an intermediate-acting neuromuscular blocking agent is given. This case report documents that it may take more than 3.5 h before it is possible to antagonize a block caused by a normal dose of rocuronium (0.6 mg kg–1). Possible causes of the extremely prolonged duration of action are discussed, as is the importance of quantitative neuromuscular monitoring.

Keywords: neuromuscular block, recovery; monitoring, neuromuscular function; neuromuscular block, rocuronium


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