Skip Navigation


BJA Advance Access originally published online on July 2, 2007
British Journal of Anaesthesia 2007 99(3):404-411; doi:10.1093/bja/aem164
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Supplementary Data
Right arrow All Versions of this Article:
99/3/404    most recent
aem164v1
Right arrow E-Letters: Submit a response to the article
Right arrow E-letters: View responses
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (2)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by De Baerdemaeker, L. E. C.
Right arrow Articles by Struys, M. M. R. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by De Baerdemaeker, L. E. C.
Right arrow Articles by Struys, M. M. R. F.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?


© The Board of Management and Trustees of the British Journal of Anaesthesia 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Influence of intraoperative opioid on postoperative pain and pulmonary function after laparoscopic gastric banding: remifentanil TCI vs sufentanil TCI in morbid obesity {dagger}

L. E. C. De Baerdemaeker1,*, S. Jacobs1, P. Pattyn2, E. P. Mortier1 and M. M. R. F. Struys1

1 Department of Anaesthesia
2 Department of Surgery, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium

* Corresponding author: Department of Anaesthesia, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium. E-mail: luc.debaerdemaeker{at}ugent.be

Background: Choice of opioid may influence postoperative pain, recovery, and respiratory homeostasis in morbid obesity. The aim of this study was to compare the effects of target-controlled infusions (TCIs) of remifentanil or sufentanil on postoperative analgesia, recovery, and pulmonary function after laparoscopic gastric banding.

Methods: Forty morbidly obese patients undergoing laparoscopic gastric banding received BIS-guided desflurane anaesthesia combined with remifentanil TCI (Group R) or sufentanil TCI (Group S). Intraoperative haemodynamic stability, BIS controllability, and immediate recovery in the operating room were measured. Pulmonary function, modified Aldrete score, modified Observers Assessment of Alertness and Sedation score, blood gas analysis, and visual analogue score for pain and postoperative nausea and vomiting were measured on admission to the post-anaesthesia care unit and 30, 60, 120 min afterwards. After operation, patients received patient-controlled analgesia with morphine.

Results: During the first two postoperative hours, cumulative morphine consumption was higher in the remifentanil group compared with the sufentanil group, but was equal values after that time. Recovery profiles and spirometry showed no significant differences. During maintenance, remifentanil gave a better haemodynamic stability.

Conclusions: As few differences occurred in the postoperative period, the theoretical advantage of remifentanil over the longer acting sufentanil can be questioned when using TCI technology.

Keywords: analgesia, anaesthetic analgesic regimens; drug delivery, computerized; lung, respiratory function; pharmacokinetics, obesity; recovery

{dagger} Performed at the Department of Anaesthesia, University Hospital of Ghent, Ghent, Belgium.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Br J AnaesthHome page
Y. Al-Tamimi, L. De Baerdemaeker, and S. Jacobs
Target controlled infusion of opioids for bariatric surgery and morphine loading dose
Br. J. Anaesth., March 1, 2009; 102(3): 432 - 433.
[Full Text] [PDF]

E-letters:

Read all E-letters

Opioid TCI for bariatric surgery
Yasir A Al-Tamimi
British Journal of Anaesthesia, 18 Nov 2008 [Full text]
Re: Opioid TCI for bariatric surgery and morphine loading dose
Luc E C De Baerdemaeker, et al.
British Journal of Anaesthesia, 11 Dec 2008 [Full text]
the problem of sample size imported from other authors
Yasir Al-Tamimi
British Journal of Anaesthesia, 15 Jan 2009 [Full text]
Re: the problem of sample size imported from other authors
Luc E De Baerdemaeker
British Journal of Anaesthesia, 5 Feb 2009 [Full text]

Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.