Skip Navigation


BJA Advance Access originally published online on October 6, 2005
British Journal of Anaesthesia 2005 95(6):798-802; doi:10.1093/bja/aei253
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
95/6/798    most recent
aei253v1
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (7)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Zhong, T.
Right arrow Articles by Li, C. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zhong, T.
Right arrow Articles by Li, C. L.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?


© The Board of Management and Trustees of the British Journal of Anaesthesia 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Comparative evaluation of the cerebral state index and the bispectral index during target-controlled infusion of propofol

T. Zhong*, Q. L. Guo, Y. D. Pang, L. F. Peng and C. L. Li

Department of Anesthesiology and Intensive Care Medicine, Xiangya Hospital, Central Southern University, Changsha 410008, China

* Corresponding author. E-mail: zhongtao88{at}tom.com

Background. Cerebral state index (CSI) has recently been introduced as an intra-operative monitor of anaesthetic depth. We compared the performance of the CSI to the bispectral index (BIS) in measuring depth of anaesthesia during target-controlled infusion (TCI) of propofol.

Methods. Twenty Chinese patients undergoing general anaesthesia were recruited. CSI and BIS, and predicted effect-site concentration of propofol were recorded. The level of sedation was tested by Modified Observer's Assessment of Alertness/Sedation Scale (MOAAS) every 20 s during stepwise increase (TCI, 0.5 µg ml–1) of propofol. The loss of verbal contact (LVC) and loss of response (LOR) were defined by MOAAS values of 2–3 and less than 2, respectively. Baseline variability and the prediction probability (PK) were calculated for the BIS and CSI. The values of BIS05 and CSI05, BIS50 and CSI50, BIS95 and CSI95 were calculated at each end-point (LVC and LOR).

Results. Baseline variability of CSI was more than that of BIS. Both CSI and BIS showed a high prediction probability for the steps awake vs LVC, awake vs LOR, and LVC vs LOR, and good correlations with MOAAS values.

Conclusion. Despite larger baseline variation, CSI performed as well as BIS in terms of PK values and correlations with step changes in sedation.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Br J AnaesthHome page
A. E. Delfino, L. I. Cortinez, C. V. Fierro, and H. R. Munoz
Propofol consumption and recovery times after bispectral index or cerebral state index guidance of anaesthesia
Br. J. Anaesth., August 1, 2009; 103(2): 255 - 259.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
R. Fuentes, L. I. Cortinez, M. M. R. F. Struys, A. Delfino, and H. Munoz
The Dynamic Relationship Between End-Tidal Sevoflurane Concentrations, Bispectral Index, and Cerebral State Index in Children
Anesth. Analg., November 1, 2008; 107(5): 1573 - 1578.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
M. Senturk, B. Gucyetmez, T. Ozkan-Seyhan, M. Karadeniz, S. Dincer, D. Akpir, T. Sengul, and T. Denkel
Comparison of the effects of thoracic and lumbar epidural anaesthesia on induction and maintenance doses of propofol during total i.v. anaesthesia
Br. J. Anaesth., August 1, 2008; 101(2): 255 - 260.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
R. E. Anderson, U. Sartipy, and J. G. Jakobsson
Use of conventional ECG electrodes for depth of anaesthesia monitoring using the cerebral state index: a clinical study in day surgery
Br. J. Anaesth., May 1, 2007; 98(5): 645 - 648.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
L. I. Cortinez, A. E. Delfino, R. Fuentes, and H. R. Munoz
Performance of the Cerebral State Index During Increasing Levels of Propofol Anesthesia: A Comparison with the Bispectral Index
Anesth. Analg., March 1, 2007; 104(3): 605 - 610.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
R. E. Anderson and J. G. Jakobsson
Cerebral state index: comparison between pairwise registrations from the left and the right sides of the brain
Br. J. Anaesth., September 1, 2006; 97(3): 347 - 350.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.