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BJA Advance Access originally published online on March 4, 2005
British Journal of Anaesthesia 2005 94(6):733-734; doi:10.1093/bja/aei101
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© The Board of Management and Trustees of the British Journal of Anaesthesia 2005. All rights reserved. For Permissions, please e-mail: journal.permissions@oupjournals.org

CASE REPORT

Transfusion for a patient of cis-AB blood type undergoing a redo cardiac operation

S. Z. Yoon, H. M. Lee, H. S. Kim, S. D. Kim, A. Y. Oh and C. S. Kim*

Department of Anaesthesiology and Pain Medicine, College of Medicine, Seoul National University, Seoul, Korea

* Corresponding author. E-mail: Monday1031{at}yahoo.co.kr

cis-AB, a rare ABO genotype, is the result of a mutated gene resulting in dual specific hybrid enzymes. A single-point mutation reverses the specificity of human blood group B synthesizing galactosyltransferase. This may lead to misclassification in ABO grouping and adverse transfusion reactions. Recently, the authors experienced a case of a patient with cis-AB blood type undergoing pulmonary valve replacement and tricuspid valvuloplasty. We transfused the patient with Rh+ A packed red blood cell, fresh frozen plasma and platelet concentrates without any clinically significant transfusion reactions.


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