Skip Navigation


BJA Advance Access originally published online on July 26, 2004
British Journal of Anaesthesia 2004 93(6):842-858; doi:10.1093/bja/aeh227
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
93/6/842    most recent
aeh227v1
Right arrow E-Letters: Submit a response to the article
Right arrow E-letters: View responses
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (24)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Mahdy, A. M.
Right arrow Articles by Webster, N. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mahdy, A. M.
Right arrow Articles by Webster, N. R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?


© The Board of Management and Trustees of the British Journal of Anaesthesia 2004

Perioperative systemic haemostatic agents

A. M. Mahdy and N. R. Webster*

Academic Unit of Anaesthesia and Intensive Care, University of Aberdeen, Aberdeen, UK

* Corresponding author: Anaesthesia and Intensive Care, Institute of Medical Sciences, Foresterhill, Aberdeen AB25 2ZD, UK. E-mail: n.r.Webster{at}abdn.ac.uk

Skilful surgery combined with blood-saving methods and careful management of blood coagulation will all help reduce unnecessary blood loss and transfusion requirements. Excessive surgical bleeding causes hypovolaemia, haemodynamic instability, anaemia and reduced oxygen delivery to tissues, with a subsequent increase in postoperative morbidity and mortality. The role of anaesthetists in managing surgical blood loss has increased greatly in the last decade. Position of the patient during surgery and the provision of a hypotensive anaesthetic regimen were once considered the most important contributions of the anaesthetist to decreasing blood loss. Now, several pharmacological haemostatic agents are being used by anaesthetists as blood-saving agents. After a brief discussion of the physiology of haemostasis, this article will review the evidence for the role of such agents in reducing perioperative blood loss and transfusion requirements.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Br J AnaesthHome page
A. Levrat, A. Gros, L. Rugeri, K. Inaba, B. Floccard, C. Negrier, and J.-S. David
Evaluation of rotation thrombelastography for the diagnosis of hyperfibrinolysis in trauma patients
Br. J. Anaesth., June 1, 2008; 100(6): 792 - 797.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
M. A. Crowther and T. E. Warkentin
Bleeding risk and the management of bleeding complications in patients undergoing anticoagulant therapy: focus on new anticoagulant agents
Blood, May 15, 2008; 111(10): 4871 - 4879.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
H. B. Bittner, J. Lemke, M. Lange, A. Rastan, and F. W. Mohr
The impact of aprotinin on blood loss and blood transfusion in off-pump coronary artery bypass grafting.
Ann. Thorac. Surg., May 1, 2008; 85(5): 1662 - 1668.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
D. J. Carlbom and B. L. Davidson
Pulmonary Embolism in the Critically Ill
Chest, July 1, 2007; 132(1): 313 - 324.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
M. A. Camarasa, G. Olle, M. Serra-Prat, A. Martin, M. Sanchez, P. Ricos, A. Perez, and L. Opisso
Efficacy of aminocaproic, tranexamic acids in the control of bleeding during total knee replacement: a randomized clinical trial
Br. J. Anaesth., May 1, 2006; 96(5): 576 - 582.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
D. Kamming and S. Clarke
Postoperative visual loss following prone spinal surgery
Br. J. Anaesth., August 1, 2005; 95(2): 257 - 260.
[Abstract] [Full Text] [PDF]

E-letters:

Read all E-letters

New Concept in Coagulation Theory.
Wilson Thomas
British Journal of Anaesthesia, 2 Mar 2005 [Full text]
Topical perioperative haemostatic agents
John W Watt, et al.
British Journal of Anaesthesia, 19 Apr 2005 [Full text]

Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.