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British Journal of Anaesthesia, 2004, Vol. 92, No. 1 121-130
© 2004 The Board of Management and Trustees of the British Journal of Anaesthesia

Review Article

Methicillin resistant Staphylococcus aureus in the critically ill

K. J. Hardy1,3, P. M. Hawkey*,1,3, F. Gao2 and B. A. Oppenheim1

1 Health Protection Agency, West Midlands Public Health Laboratory, and 2 Intensive Care Unit, Heartlands Hospital, Bordesley Green East, Birmingham, B9 5SS, UK. 3 The Department of Infection and Immunity, The Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

*Corresponding author. E-mail: peter.hawkey@heartsol.wmids.nhs.uk

Methicillin resistant Staphylococcus aureus (MRSA) is endemic within many hospitals worldwide. Critically ill patients on intensive care units have increased risk factors making them especially prone to nosocomially acquired infections. This review addresses the current situation regarding the evolution of MRSA and the techniques for identifying and epidemiologically typing it. It discusses specific risk factors, the morbidity and mortality associated with critically ill patients, and possibilities for future antibiotic treatments.

Br J Anaesth 2004; 92: 121–30


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