Skip Navigation

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (5)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Price, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Price, G.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, 2003, Vol. 91, No. 6 909-910
© 2003 The Board of Management and Trustees of the British Journal of Anaesthesia

Case Reports

Metformin lactic acidosis, acute renal failure and rofecoxib

G. Price*,

Department of Anaesthesia, Victoria Hospital, Kirkcaldy, Fife, Scotland, UK

*Present address: Department of Intensive Care The St George Hospital, Kogarah, Sydney, Australia. E-mail: grantcprice@hotmail.com

A patient with acute renal failure associated with lactic acidosis as a result of concurrent treatment with metformin is described. Rofecoxib may have been a precipitating factor. The risk of renal failure with the use of traditional NSAIDs is well known. However, what is less well appreciated is the role that the COX 2 inhibitors may play in the development of renal failure which, when it occurs in a patient on metformin, can lead to a potentially disastrous outcome.

Br J Anaesth 2003; 91: 909–10


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 BMJHome page
A. James
NSAIDs and renin-angiotensin-aldosterone system
BMJ, December 23, 2009; 339(dec23_1): b5567 - b5567.
[Full Text]

Home page
 BMJHome page
E. Fitzgerald, S. Mathieu, and A. Ball
Metformin associated lactic acidosis
BMJ, September 16, 2009; 339(sep16_2): b3660 - b3660.
[Full Text]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.