Skip Navigation

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (5)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Vesely, A.
Right arrow Articles by Sasano, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Vesely, A.
Right arrow Articles by Sasano, H.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, 2003, Vol. 91, No. 6 787-792
© 2003 The Board of Management and Trustees of the British Journal of Anaesthesia

Clinical Investigations

Isocapnic hyperpnoea accelerates recovery from isoflurane anaesthesia

A. Vesely1, J. A. Fisher*,1, N. Sasano1,2, D. Preiss1, R. Somogyi1, H. El-Beheiry1, A. Prabhu1 and H. Sasano1,2

1 Department of Anesthesia, University Health Network, University of Toronto, Toronto, Canada, M5G 2C4 2 Present address: Department of Anesthesiology and Resuscitology, Nagoya City University Medical School, Nagoya, 467-8601, Japan

*Corresponding author. E-mail joe.fisher @utoronto.ca

Background. Hyperventilation should speed up elimination of volatile anaesthetic agents from the body, but hyperventilation usually results in hypocapnia. We compared recovery from isoflurane anaesthesia in patients allowed to recover with assisted spontaneous ventilation (control) and those treated with isocapnic hyperpnoea.

Methods. Fourteen patients were studied after approximately 1 h of anaesthesia with isoflurane. Control patients were allowed to recover in the routine way. Isocapnic hyperpnoea patients received 2–3 times their intraoperative ventilation using a system to maintain end tidal PCO2 at 45–50 mm Hg. We measured time to removal of the airway and rate of change of bispectral index (BIS) during recovery.

Results. With isocapnic hyperpnoea, the time to removal of the airway was markedly less (median and interquartile range values of 3.6 (2.7–3.7) vs 12.1 (6.8–17.2) min, P<0.001); mean (SD) BIS slopes during recovery were 11.8 (4.4) vs 4.3 (2.7) min–1 (P<0.01) for isocapnic hyperpnoea and control groups, respectively. Isocapnic hyperpnoea was easily applied in the operating room.

Conclusions. Isocapnic hyperpnoea at the end of surgery results in shorter and less variable time to removal of the airway after anaesthesia with isoflurane and nitrous oxide.

Br J Anaesth 2003; 91: 787–92


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Canadian J. AnesthesiaHome page
R. Katznelson, A. Van Rensburg, L. Minkovich, Z. Friedman, M. Wasowicz, and J. Fisher
475241 - ISOCAPNIC HYPERPNOEA AND RECOVERY TIME AFTER ANESTHESIA WITH ISOFLURANE
Can J Anesth, June 1, 2008; 55(suppl_1): 475241 - 475241.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
R. Katznelson, L. Minkovich, Z. Friedman, L. Fedorko, W. S. Beattie, and J. A. Fisher
Accelerated Recovery from Sevoflurane Anesthesia with Isocapnic Hyperpnoea
Anesth. Analg., February 1, 2008; 106(2): 486 - 491.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
D. J. Sakata, N. A. Gopalakrishnan, J. A. Orr, J. L. White, and D. R. Westenskow
Rapid Recovery from Sevoflurane and Desflurane with Hypercapnia and Hyperventilation
Anesth. Analg., July 1, 2007; 105(1): 79 - 82.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
N. A. Gopalakrishnan, D. J. Sakata, J. A. Orr, S. McJames, and D. R. Westenskow
Hypercapnia Shortens Emergence Time from Inhaled Anesthesia in Pigs
Anesth. Analg., April 1, 2007; 104(4): 815 - 821.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
D. J. Sakata, N. A. Gopalakrishnan, J. A. Orr, J. L. White, and D. R. Westenskow
Hypercapnic Hyperventilation Shortens Emergence Time from Isoflurane Anesthesia
Anesth. Analg., March 1, 2007; 104(3): 587 - 591.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
E. I. Eger II and L. J. Saidman
Illustrations of Inhaled Anesthetic Uptake, Including Intertissue Diffusion to and from Fat
Anesth. Analg., April 1, 2005; 100(4): 1020 - 1033.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.