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British Journal of Anaesthesia, 2003, Vol. 90, No. 1 72-83
© 2003 The Board of Management and Trustees of the British Journal of Anaesthesia

Severe meningococcal disease in childhood

P. B. Baines{dagger},*,1 and C. A. Hart2

1 Paediatric Intensive Care Unit, Royal Liverpool Children’s Hospital, Eaton Road, Liverpool L12 2AP, UK. 2 Department of Medical Microbiology and Genitourinary Medicine, Duncan Building, Royal Liverpool University Hospital, Daulby Street, Liverpool L69 3GA, UK*Corresponding author. E-mail: paul.baines@rlch-tr.nwest.nhs.uk

{dagger}Declaration of interest. Paul Baines was supported by the Johanne Holly Meningitis Fund for part of the time that this review was in preparation.

Abstract

Meningococcal disease remains an important cause of illness in the UK (Commun Dis Rep CDR Suppl 1999; 9: S5), and is the commonest infective cause of death in children outwith the neonatal period. Although most common in children, adults are also affected. Meningococcal vaccines offer long-term protection only against Group C disease, which causes less than half of invasive meningococcal disease (Commun Dis Rep CDR Wkly 1998; 8: 2) in the UK.

Br J Anaesth 2003; 90: 72–83


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