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British Journal of Anaesthesia, 2001, Vol. 87, No. 5 770-771
© 2001 The Board of Management and Trustees of the British Journal of Anaesthesia

Short Communications

ADCON-L and hypotension during lumbar microdiscectomy

S. Kalogrianitis1, P. Barrett2 and I. Shackleford2

1Department of Musculoskeletal Science, Royal Liverpool University Hospital, Liverpool L69 3GA, UK. 2Warrington Hospital, Lovely Lane, Warrington WA5 IQG, UK*Corresponding author

ADCON-L anti-adhesion gel is used as an antifibrotic agent in surgery for herniated lumbar disc. We report seven patients undergoing lumbar microdiscectomy, in whom ADCON-L gel was applied to the nerve root before closure of the surgical site. After the administration of ADCON-L, tachycardia and hypotension were noted, and were quickly and effectively reversed by i.v. fluids and ephedrine. Since its routine introduction into our practice, we have given ADCON-L on 212 occasions, with an incidence of adverse haemodynamic reactions of 3.3%. Adverse cardiovascular reactions do not appear to have been reported before.

Br J Anaesth 2001; 87: 770–1


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