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British Journal of Anaesthesia, 2001, Vol. 86, No. 5 674-677
© 2001 The Board of Management and Trustees of the British Journal of Anaesthesia

Double-blind comparison of ropivacaine 7.5 mg ml–1 with bupivacaine 5 mg ml–1 for sciatic nerve block

C. Connolly, D. M. Coventry and J. A. W. Wildsmith

Department of Anaesthesia, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK*Corresponding author

Two groups of 12 patients had a sciatic nerve block performed with 20 ml of either ropivacaine 7.5 mg ml–1 or bupivacaine 5 mg ml–1. There was no statistically significant difference in the mean time to onset of complete anaesthesia of the foot or to first request for post-operative analgesia. The quality of the block was the same in each group. Although there was no statistically significant difference in the mean time to peak plasma concentrations the mean peak concentration of ropivacaine was significantly higher than that of bupivacaine. There were no signs of systemic local anaesthetic toxicity in any patient in either group.

Br J Anaesth 2001; 86: 674–7


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