Skip Navigation

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (20)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Hirsch, N. P.
Right arrow Articles by Radcliffe, J. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hirsch, N. P.
Right arrow Articles by Radcliffe, J. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, 2001, Vol. 86, No. 4 555-564
© 2001 The Board of Management and Trustees of the British Journal of Anaesthesia

Neurofibromatosis: clinical presentations and anaesthetic implications

N. P. Hirsch1, A. Murphy1,2 and J. J. Radcliffe1,3

1The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK*Corresponding authorPresent addresses: 2Department of Anaesthesia, Singleton Hospital, Sketty, Swansea SA2 8QA, UK and 3Department of Anaesthesia and Critical Care, King’s College Hospital, Denmark Hill, London SE5 9RF, UK

The neurofibromatoses are autosomal dominant diseases that have widespread effects on ectodermal and mesodermal tissue. The commonest member of the group is neurofibromatosis type 1 (NF1) which varies in severity but which can affect all physiological systems. Neurofibromas are the characteristic lesions of the condition and not only occur in the neuraxis but may also be found in the oropharnyx and larynx; these may produce difficulties with laryngoscopy and tracheal intubation. Pulmonary pathology includes pulmonary fibrosis and cystic lung disease. The cardiovascular manifestations of NF1 include hypertension, which may be associated with phaeochromocytoma or renal artery stenosis. Neurofibromas may also affect the gastrointestinal tract and carcinoid tumours may be found in the duodenum. This review documents the aetiology and clinical manifestations of the neurofibromatoses and discusses their relevance to the anaesthetist.

Br J Anaesth 2001; 86: 555–64


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 PERSPECT VASC SURG ENDOVASC THERHome page
W. A. Oldenburg
Commentary on "Inferior Mesenteric Artery Aneurysm Combined With Renal Artery Stenosis in a Patient with Neurofibromatosis"
Perspectives in Vascular Surgery and Endovascular Therapy, September 1, 2006; 18(3): 224 - 225.
[PDF]

Home page
 Arch Otolaryngol Head Neck SurgHome page
R. Rahbar, B. G. Litrovnik, S. O. Vargas, C. D. Robson, R. C. Nuss, M. B. Irons, T. J. McGill, and G. B. Healy
The Biology and Management of Laryngeal Neurofibroma
Arch Otolaryngol Head Neck Surg, December 1, 2004; 130(12): 1400 - 1406.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
M. D. Esler, J. Durbridge, and S. Kirby
Epidural haematoma after dural puncture in a parturient with neurofibromatosis
Br. J. Anaesth., December 1, 2001; 87(6): 932 - 934.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.